8. Benzocaine has been tested as an an aesthetic for

Question

8. Benzocaine has been tested as an an aesthetic for inhibition of m1 muscarinic acetylcholine signalling. Using the data below, plot a graph and determine the IC50. 20 marks Concentration (M)

1 x 10-6 10 x 10-6 100 x 10-6 1000 x 10-6 10000 x 10-6 100000 x 10-6 % of control response 97 93 78 56 42 36

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